May 8, 1997 · Rami Kaib - Player profile 22/23 | Transfermarkt #13 Rami Kaib Heerenveen Eredivisie League level: First Tier Joined: Jan 13, 2021 Contract expires: Jun 30, 2024 imago images + Date of birth/Age: May 8, 1997 (25) …
List of domain same IP 217.160.223.151
KaiC is a gene belonging to the KaiABC gene cluster (with KaiA, and KaiB) that, together, regulate bacterial circadian rhythms, specifically in cyanobacteria. KaiC encodes for the KaiC protein which interacts with the KaiA and KaiB proteins in a post-translational oscillator (PTO).
What is the KaiABC gene cluster?Takao Kondo, Susan S. Golden, and Carl H. Johnson discovered the gene cluster in 1998 and named the gene cluster kaiABC, as "kai" means “cycle” in Japanese. They generated 19 different clock mutants that were mapped to kaiA, kaiB, and kaiC genes, and successfully cloned the gene cluster in the cyanobacteria Synechococcus elongatus.
What is the role of KaiC in transcription regulation?The hexameric rings of KaiC closely resembles RecA, with 8 α-helices surrounding a twisted β-sheet made up of 7 strands. This structure favours the binding of a nucleotide at the carboxy-end of the β-sheet. KaiC’s structural similarities to these proteins suggests a role for KaiC in transcription regulation.
What controls the oscillation rate of kaiBC promoter?This oscillation rate is thought to be controlled by the ratio of phosphorylated to unphosphorylated KaiC protein. KaiC phosphorylation ratio is a main factor in the activation of kaiBC promoter as well.
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