Sdha.ca - SDHA gene: MedlinePlus Genetics

Provided by Alexa ranking, sdha.ca has ranked N/A in N/A and 6,950,224 on the world. sdha.ca reaches roughly 444 users per day and delivers about 13,311 users each month. The domain sdha.ca uses a Commercial suffix and it's server(s) are located in N/A with the IP number 198.169.132.25 and it is a .ca domain.

WEBThe SDHA gene is a tumor suppressor gene, which means it prevents cells from growing and dividing in an uncontrolled way. The SDHA gene provides instructions for making one of four parts (subunits) of the succinate dehydrogenase (SDH) enzyme. Learn about this gene and related health conditions.

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SDHA gene: MedlinePlus Genetics
medlineplus.gov

https://medlineplus.gov/genetics/gene/sdha/

WEBThe SDHA gene is a tumor suppressor gene, which means it prevents cells from growing and dividing in an uncontrolled way. The SDHA gene provides instructions for making one of four parts (subunits) of the succinate dehydrogenase (SDH) enzyme. Learn about this gene and related health conditions.

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SDHA Gene - GeneCards | SDHA Protein | SDHA Antibody
genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=SDHA

WEBApr 3, 2024 · GeneCards Summary for SDHA Gene. SDHA (Succinate Dehydrogenase Complex Flavoprotein Subunit A) is a Protein Coding gene. Diseases associated with SDHA include Cardiomyopathy, Dilated, 1Gg and Mitochondrial Complex Ii Deficiency, Nuclear Type 1 . Among its related pathways are TCA cycle III (animals) and …

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International consensus on initial screening and follow-up of ... - Nature
nature.com

https://www.nature.com/articles/s41574-021-00492-3

WEBMay 21, 2021 · 76 Citations. 46 Altmetric. Metrics. Abstract. Approximately 20% of patients diagnosed with a phaeochromocytoma or paraganglioma carry a germline mutation in one of the succinate dehydrogenase (...

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SDHA - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/SDHA

WEBThe SDHA gene is located on the p arm of chromosome 5 at locus 15 and is composed of 16 exons. The SDHA protein encoded by this gene is 664 amino acids long and weighs 72.7 kDA. SDHA protein has four subdomains, including capping domain, helical domain, C-terminal domain and most notably, β-barrel FAD-binding domain at N-terminus.

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About SDHA Gene Mutations - University of Utah
utah.edu

https://hci-portal.hci.utah.edu/sites/factsheets/Shared%20Documents/about-sdha-gene-mutations.pdf

WEBThe SDH genes have instructions for turning food into energy and helping fix mistakes in DNA. The four genes involved are SDHA, SDHB, SDHC, and SDHD. If there is a mutation in one of these genes, it can cause cells to grow and divide too much. This can lead to tumors called paragangliomas and pheochromocytomas.

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Understanding Your Positive SDHA Genetic Test Result
ambrygen.com

https://www.ambrygen.com/file/material/view/1883/SDHA%20Positive%20Understanding%20Your%20Results%20%2817216_0%29.pdf

WEBSDHA . Mutation Lifetime Cancer Risks* CUMULATIVE LIFETIME RISK (%) PGL/PCC. GENERAL POPULATION. 0. 20. 40. 60. 80 * Because risk estimates vary in different studies, only approximate risks are . given. Cancer risks will differ based on individual and family history. Has . SDHA . mutation No. SDHA . High End of . mutation

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Germline SDHA mutations in children and adults with cancer
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071569/

WEBDec 20, 2017 · This study revealed germline SDHA mutations in patients with the following cancer diagnoses: neuroblastoma, pheochromocytoma, melanoma, breast cancer, colon cancer, renal cell carcinoma, prostate cancer, gastric cancer, and endometrial cancer. Supporting biochemical evidence in this study is illustrated for neuroblastoma and GIST.

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SDHA - My Cancer Genome
mycancergenome.org

https://www.mycancergenome.org/content/gene/sdha/

WEBOverview. Succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA) is a gene that encodes a catalytic protein that is a member of succinate-ubiquinone oxidoreductase. The complex participates in the mitochondrial respiratory chain.

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SDHA Mutation - My Cancer Genome
mycancergenome.org

https://www.mycancergenome.org/content/alteration/sdha-mutation/

WEBSignificance of SDHA Mutation in Diseases. Gastrointestinal Stromal Tumor +. Malignant Solid Tumor +. Renal Cell Carcinoma +. Papillary Renal Cell Carcinoma +. Non-Small Cell Lung Carcinoma +. Clear Cell Renal Cell Carcinoma +. Leiomyosarcoma +. Osteosarcoma +. Breast Carcinoma +. Peritoneal Mesothelioma +. Pleural Mesothelioma +. References. 1.

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Clinical, Diagnostic, and Treatment Characteristics of SDHA …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395427/

WEBFeb 22, 2019 · The SDH (succinate dehydrogenase) respiratory complex with a role in the Krebs cycle and oxidative phosphorylation ( 6) has four subunits encoded by 4 SDHx genes- SDHA, SDHB, SDHC, and SDHD that act as tumor suppressors ( 7 – 15 ). Initially, the SDHA gene had been associated only with Leigh syndrome ( 4, 16 ).

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Host	Type	Class	TTL	Extra
sdha.ca	HINFO	IN	3600	Cpu: RFC8482 Os:

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IP	198.169.132.25
Domain infomation	Domain Name: sdha.ca Registry Domain ID: D53310-CIRA Registrar WHOIS Server: whois.ca.fury.ca Registrar URL: https://help.opensrs.com/hc/en-us Updated Date: 2023-11-16T15:48:34Z Creation Date: 2000-11-22T04:10:11Z Registry Expiry Date: 2024-12-01T05:00:00Z Registrar: Tucows.com Co. Registrar IANA ID: not applicable Registrar Abuse Contact Email: [email protected] Registrar Abuse Contact Phone: +1.4165350123 Domain Status: clientTransferProhibited https://icann.org/epp#clientTransferProhibited Domain Status: clientUpdateProhibited https://icann.org/epp#clientUpdateProhibited Registry Registrant ID: R37883-CIRA Registrant Name: Saskatchewan Dental Hygienists Association Registrant Organization: Registrant Street: 114-3502 Taylor Street East Registrant City: Saskatoon Registrant State/Province: SK Registrant Postal Code: S7H5H9 Registrant Country: CA Registrant Phone: +1.3069317342 Registrant Phone Ext: Registrant Fax: Registrant Fax Ext: Registrant Email: [email protected] Registry Admin ID: 2805913-CIRA Admin Name: Kellie Hildebrandt Admin Organization: Saskatchewan Dental Hygienists Association Admin Street: 114-3502 Taylor Street East Admin City: Saskatoon Admin State/Province: SK Admin Postal Code: S7H5H9 Admin Country: CA Admin Phone: +1.3069317342 Admin Phone Ext: Admin Fax: Admin Fax Ext: Admin Email: [email protected] Registry Tech ID: 2805799-CIRA Tech Name: Kellie Hildebrandt Tech Organization: Saskatchewan Dental Hygienists Association Tech Street: 114-3502 Taylor Street East Tech City: Saskatoon Tech State/Province: SK Tech Postal Code: S7H5H9 Tech Country: CA Tech Phone: +1.3069317342 Tech Phone Ext: Tech Fax: Tech Fax Ext: Tech Email: [email protected] Registry Billing ID: Billing Name: Billing Organization: Billing Street: Billing City: Billing State/Province: Billing Postal Code: Billing Country: Billing Phone: Billing Phone Ext: Billing Fax: Billing Fax Ext: Billing Email: Name Server: beth.ns.cloudflare.com Name Server: rick.ns.cloudflare.com DNSSEC: unsigned URL of the ICANN Whois Inaccuracy Complaint Form: https://www.icann.org/wicf/ >>> Last update of WHOIS database: 2024-04-23T15:44:56Z <<< For more information on Whois status codes, please visit https://icann.org/epp % % Use of CIRA's WHOIS service is governed by the Terms of Use in its Legal % Notice, available at http://www.cira.ca/legal-notice/?lang=en % % (c) 2024 Canadian Internet Registration Authority, (http://www.cira.ca/)